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Three-dimensional direct measurement of cardiomyocyte volume, nuclearity, and ploidy in thick histological sections

Quantitative assessment of myocardial development and disease requires accurate measurement of cardiomyocyte volume, nuclearity (nuclei per cell), and ploidy (genome copies per cell). Current methods require enzymatically isolating cells, which excludes the use of archived tissue, or serial sectioni...

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Detalles Bibliográficos
Autores principales: Bensley, Jonathan Guy, De Matteo, Robert, Harding, Richard, Black, Mary Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822151/
https://www.ncbi.nlm.nih.gov/pubmed/27048757
http://dx.doi.org/10.1038/srep23756