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Immunization with a novel Clostridium perfringens epsilon toxin mutant rETX(Y196E)-C confers strong protection in mice

Epsilon toxin (ETX) is produced by toxinotypes B and D of Clostridium perfringens. It can induce lethal enterotoxemia in domestic animals, mainly in sheep, goats and cattle, causing serious economic losses to global animal husbandry. In this study, a novel and stable epsilon toxin mutant rETX(Y196E)...

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Detalles Bibliográficos
Autores principales:	Yao, Wenwu, Kang, Jingjing, Kang, Lin, Gao, Shan, Yang, Hao, Ji, Bin, Li, Ping, Liu, Jing, Xin, Wenwen, Wang, Jinglin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822168/ https://www.ncbi.nlm.nih.gov/pubmed/27048879 http://dx.doi.org/10.1038/srep24162

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