Deletion of BMP receptor type IB decreased bone mass in association with compromised osteoblastic differentiation of bone marrow mesenchymal progenitors

We previously found that disruption of two type I BMP receptors, Bmpr1a and Acvr1, respectively, in an osteoblast-specific manner, increased bone mass in mice. BMPR1B, another BMP type I receptor, is also capable of binding to BMP ligands and transduce BMP signaling. However, little is known about t...

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Detalles Bibliográficos
Autores principales: Shi, Ce, Iura, Ayaka, Terajima, Masahiko, Liu, Fei, Lyons, Karen, Pan, Haichun, Zhang, Honghao, Yamauchi, Mitsuo, Mishina, Yuji, Sun, Hongchen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822175/
https://www.ncbi.nlm.nih.gov/pubmed/27048979
http://dx.doi.org/10.1038/srep24256

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