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Targeted resequencing and variant validation using pxlence PCR assays

The advent of next-generation sequencing technologies had a profound impact on molecular diagnostics. PCR is a popular method for target enrichment of disease gene panels. Using our proprietary primer-design pipeline, primerXL, we have created almost one million assays covering over 98% of the human...

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Detalles Bibliográficos
Autores principales:	Coppieters, Frauke, Verniers, Kimberly, De Leeneer, Kim, Vandesompele, Jo, Lefever, Steve
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822215/ https://www.ncbi.nlm.nih.gov/pubmed/27077044 http://dx.doi.org/10.1016/j.bdq.2015.09.001

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