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Proximity assays for sensitive quantification of proteins
Proximity assays are immunohistochemical tools that utilise two or more DNA-tagged aptamers or antibodies binding in close proximity to the same protein or protein complex. Amplification by PCR or isothermal methods and hybridisation of a labelled probe to its DNA target generates a signal that enab...
Autores principales: | Greenwood, Christina, Ruff, David, Kirvell, Sara, Johnson, Gemma, Dhillon, Harvinder S., Bustin, Stephen A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822221/ https://www.ncbi.nlm.nih.gov/pubmed/27077033 http://dx.doi.org/10.1016/j.bdq.2015.04.002 |
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