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Safety and tolerability of BAN2401 - a clinical study in Alzheimer’s disease with a protofibril selective Aβ antibody
BACKGROUND: Several monoclonal antibodies for the treatment of Alzheimer’s disease (AD) have been in development over the last decade. BAN2401 is a monoclonal antibody that selectively binds soluble amyloid β (Aβ) protofibrils. METHODS: Here we describe the first clinical study with BAN2401. Safety...
Autores principales: | Logovinsky, Veronika, Satlin, Andrew, Lai, Robert, Swanson, Chad, Kaplow, June, Osswald, Gunilla, Basun, Hans, Lannfelt, Lars |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822297/ https://www.ncbi.nlm.nih.gov/pubmed/27048170 http://dx.doi.org/10.1186/s13195-016-0181-2 |
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