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Quaternary structure of a G-protein-coupled receptor heterotetramer in complex with G(i) and G(s)

BACKGROUND: G-protein-coupled receptors (GPCRs), in the form of monomers or homodimers that bind heterotrimeric G proteins, are fundamental in the transfer of extracellular stimuli to intracellular signaling pathways. Different GPCRs may also interact to form heteromers that are novel signaling unit...

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Detalles Bibliográficos
Autores principales:	Navarro, Gemma, Cordomí, Arnau, Zelman-Femiak, Monika, Brugarolas, Marc, Moreno, Estefania, Aguinaga, David, Perez-Benito, Laura, Cortés, Antoni, Casadó, Vicent, Mallol, Josefa, Canela, Enric I., Lluís, Carme, Pardo, Leonardo, García-Sáez, Ana J., McCormick, Peter J., Franco, Rafael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822319/ https://www.ncbi.nlm.nih.gov/pubmed/27048449 http://dx.doi.org/10.1186/s12915-016-0247-4

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