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Secreted frizzled related protein 1 protects H9C2 cells from hypoxia/re-oxygenation injury by blocking the Wnt signaling pathway

BACKGROUND: In animal models, secreted frizzled related protein 1 (Sfrp1) inhibition of the Wnt signaling pathway is beneficial because Sfrp1 reduces myocardial apoptosis and prevents heart failure. The mechanisms mediating the cellular survival effect of Sfrp1 has not been completely elucidated. Th...

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Detalles Bibliográficos
Autores principales: Tao, Jing, Abudoukelimu, Mayila, Ma, Yi-tong, Yang, Yi-ning, Li, Xiao-mei, Chen, Bang-dang, Liu, Fen, He, Chun-hui, Li, Hua-yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822324/
https://www.ncbi.nlm.nih.gov/pubmed/27048460
http://dx.doi.org/10.1186/s12944-016-0240-5