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Immune Checkpoint Blockade to Improve Tumor Infiltrating Lymphocytes for Adoptive Cell Therapy

Tumor-infiltrating lymphocytes (TIL) has been associated with improved survival in cancer patients. Within the tumor microenvironment, regulatory cells and expression of co-inhibitory immune checkpoint molecules can lead to the inactivation of TIL. Hence, there is a need to develop strategies that d...

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Detalles Bibliográficos
Autores principales:	Kodumudi, Krithika N., Siegel, Jessica, Weber, Amy M., Scott, Ellen, Sarnaik, Amod A., Pilon-Thomas, Shari
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822778/ https://www.ncbi.nlm.nih.gov/pubmed/27050669 http://dx.doi.org/10.1371/journal.pone.0153053

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