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Loss of 5-Hydroxymethylcytosine Is an Independent Unfavorable Prognostic Factor for Esophageal Squamous Cell Carcinoma

Ten-eleven translocation (TET) enzymes catalyze the oxidation of 5-methylcytosine (5-mC) to 5-hydroxymethylcytosine (5-hmC), 5-formylcytosine and 5-carboxylcytosine, which result in genomic DNA demethylation. It was reported that 5-hmC levels were decreased in a variety of cancers and could be regar...

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Detalles Bibliográficos
Autores principales:	Shi, Xuejiao, Yu, Yue, Luo, Mei, Zhang, Zhirong, Shi, Susheng, Feng, Xiaoli, Chen, Zhaoli, He, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822830/ https://www.ncbi.nlm.nih.gov/pubmed/27050164 http://dx.doi.org/10.1371/journal.pone.0153100

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