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Joint Estimation of Contamination, Error and Demography for Nuclear DNA from Ancient Humans
When sequencing an ancient DNA sample from a hominin fossil, DNA from present-day humans involved in excavation and extraction will be sequenced along with the endogenous material. This type of contamination is problematic for downstream analyses as it will introduce a bias towards the population of...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822957/ https://www.ncbi.nlm.nih.gov/pubmed/27049965 http://dx.doi.org/10.1371/journal.pgen.1005972 |