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VDAC3 as a sensor of oxidative state of the intermembrane space of mitochondria: the putative role of cysteine residue modifications

Voltage-Dependent Anion selective Channels (VDAC) are pore-forming mitochondrial outer membrane proteins. In mammals VDAC3, the least characterized isoform, presents a set of cysteines predicted to be exposed toward the intermembrane space. We find that cysteines in VDAC3 can stay in different oxida...

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Detalles Bibliográficos
Autores principales: Reina, Simona, Checchetto, Vanessa, Saletti, Rosaria, Gupta, Ankit, Chaturvedi, Deepti, Guardiani, Carlo, Guarino, Francesca, Scorciapino, Mariano Andrea, Magrì, Andrea, Foti, Salvatore, Ceccarelli, Matteo, Messina, Angela Anna, Mahalakshmi, Radhakrishnan, Szabo, Ildiko, De Pinto, Vito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823033/
https://www.ncbi.nlm.nih.gov/pubmed/26760765
http://dx.doi.org/10.18632/oncotarget.6850

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