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MicroRNA-497 inhibits tumor growth and increases chemosensitivity to 5-fluorouracil treatment by targeting KSR1

Colorectal cancer (CRC) is one of the leading cancer-related causes of death in the world. Recently, downregulation of microRNA-497 (miR-497) has been observed in CRC tissues. In this study, we found that miR-497 expression levels were downregulated in human CRC specimens compared to the adjacent no...

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Detalles Bibliográficos
Autores principales: Wang, Lin, Jiang, Cheng-fei, Li, Dong-mei, Ge, Xin, Shi, Zhu-mei, Li, Chong-yong, Liu, Xue, Yin, Yu, Zhen, Linlin, Liu, Ling-Zhi, Jiang, Bing-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823062/
https://www.ncbi.nlm.nih.gov/pubmed/26673620
http://dx.doi.org/10.18632/oncotarget.6545