Melatonin inhibits AP-2β/hTERT, NF-κB/COX-2 and Akt/ERK and activates caspase/Cyto C signaling to enhance the antitumor activity of berberine in lung cancer cells

Melatonin, a molecule produced throughout the animal and plant kingdoms, and berberine, a plant derived agent, both exhibit antitumor and multiple biological and pharmacological effects, but they have never been combined altogether for the inhibition of human lung cancers. In this study, we investig...

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Detalles Bibliográficos
Autores principales: Lu, Jian-Jun, Fu, Lingyi, Tang, Zhipeng, Zhang, Changlin, Qin, Lijun, Wang, Jingshu, Yu, Zhenlong, Shi, Dingbo, Xiao, Xiangsheng, Xie, Fangyun, Huang, Wenlin, Deng, Wuguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823085/
https://www.ncbi.nlm.nih.gov/pubmed/26672764
http://dx.doi.org/10.18632/oncotarget.6407

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