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Identification of a novel HER3 activating mutation homologous to EGFR-L858R in lung cancer

Somatic mutations found within the tyrosine kinase domain (TKD) of the human epidermal growth factor (HER) family of receptors have been implicated in the development and progression of non-small cell lung cancer (NSCLC). However, no conclusive reports have described pathogenic mutations in kinase-i...

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Detalles Bibliográficos
Autores principales:	Umelo, Ijeoma, Noeparast, Amir, Chen, Gang, Renard, Marleen, Geers, Caroline, Vansteenkiste, Johan, Giron, Philippe, De Wever, Olivier, Teugels, Erik, De Grève, Jacques
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823091/ https://www.ncbi.nlm.nih.gov/pubmed/26689995 http://dx.doi.org/10.18632/oncotarget.6585

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