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Quinomycin A targets Notch signaling pathway in pancreatic cancer stem cells

Cancer stem cells (CSCs) appear to explain many aspects of the neoplastic evolution of tumors and likely account for enhanced therapeutic resistance following treatment. Dysregulated Notch signaling, which affects CSCs plays an important role in pancreatic cancer progression. We have determined the...

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Detalles Bibliográficos
Autores principales: Ponnurangam, Sivapriya, Dandawate, Prasad R., Dhar, Animesh, Tawfik, Ossama W., Parab, Rajashri R., Mishra, Prabhu Dutt, Ranadive, Prafull, Sharma, Rajiv, Mahajan, Girish, Umar, Shahid, Weir, Scott J., Sugumar, Aravind, Jensen, Roy A., Padhye, Subhash B., Balakrishnan, Arun, Anant, Shrikant, Subramaniam, Dharmalingam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823101/
https://www.ncbi.nlm.nih.gov/pubmed/26673007
http://dx.doi.org/10.18632/oncotarget.6560

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