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Sphingosine kinase 1 is overexpressed and promotes adrenocortical carcinoma progression

Adrenocortical carcinoma (ACC) is a rare endocrine tumor with a very poor prognosis. Sphingosine kinase 1 (SphK1), an oncogenic kinase, has previously been found to be upregulated in various cancers. However, the role of the SphK1 in ACC has not been investigated. In this study, SphK1 mRNA and prote...

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Detalles Bibliográficos
Autores principales: Xu, Yunze, Dong, Baijun, Huang, Jiwei, Kong, Wen, Xue, Wei, Zhu, Yu, Zhang, Jin, Huang, Yiran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823102/
https://www.ncbi.nlm.nih.gov/pubmed/26673009
http://dx.doi.org/10.18632/oncotarget.6564