Artemin is hypoxia responsive and promotes oncogenicity and increased tumor initiating capacity in hepatocellular carcinoma

Hypoxia has been reported to regulate the cancer stem cell (CSC) population yet the underlying mechanism is poorly characterized. Herein, we show that Artemin (ARTN), a member of the glial cell derived neurotrophic factor family of ligands, is a hypoxia-responsive factor and is essential for hypoxia...

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Detalles Bibliográficos
Autores principales: Zhang, Min, Zhang, Weijie, Wu, Zhengsheng, Liu, Shumin, Sun, Linchong, Zhong, Yanghao, Zhang, Xiao, Kong, Xiangjun, Qian, Pengxu, Zhang, Huafeng, Lobie, Peter E., Zhu, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823105/
https://www.ncbi.nlm.nih.gov/pubmed/26675549
http://dx.doi.org/10.18632/oncotarget.6572

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