EGFR kinase domain mutation positive lung cancers are sensitive to intrapleural perfusion with hyperthermic chemotherapy (IPHC) complete treatment

Lung cancer is the global leading cause of cancer-related deaths. A significant portion of lung cancer patients harbor kinase domain mutations in the epidermal growth factor receptor (EGFR). While EGFR tyrosine kinase inhibitors (TKI) effectively shrink tumors harboring mutant EGFR, clinical efficac...

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Detalles Bibliográficos
Autores principales: Zhang, Hongjuan, Zhan, Cheng, Ke, Ji, Xue, Zhiqiang, Zhang, Aiqun, Xu, Kaifeng, Shen, Zhirong, Yu, Lei, Chen, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823112/
https://www.ncbi.nlm.nih.gov/pubmed/26654941
http://dx.doi.org/10.18632/oncotarget.6491

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