Auranofin-mediated inhibition of PI3K/AKT/mTOR axis and anticancer activity in non-small cell lung cancer cells

Auranofin, a gold complex that has been used to treat rheumatoid arthritis in clinics and has documented pharmacokinetic and safety profiles in humans, has recently been investigated for its anticancer activity in leukemia and some solid cancers. However, auranofin's single agent activity in lu...

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Detalles Bibliográficos
Autores principales: Li, Hongyu, Hu, Jing, Wu, Shuhong, Wang, Li, Cao, Xiaobo, Zhang, Xiaoshan, Dai, Bingbing, Cao, Mengru, Shao, Ruping, Zhang, Ran, Majidi, Mourad, Ji, Lin, Heymach, John V., Wang, Michael, Pan, Shiyang, Minna, John, Mehran, Reza J., Swisher, Stephen G., Roth, Jack A., Fang, Bingliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823126/
https://www.ncbi.nlm.nih.gov/pubmed/26657290
http://dx.doi.org/10.18632/oncotarget.6516

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