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The TGF-β/SMAD pathway is an important mechanism for NK cell immune evasion in childhood B acute lymphoblastic leukemia

Natural killer (NK) cells are key components of the innate immune system, providing potent antitumor immunity. Here, we show that the TGF-β/SMAD signaling pathway is an important mechanism for NK cell immune evasion in childhood B-acute lymphoblastic leukemia (ALL). We characterized NK cells in 50 c...

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Detalles Bibliográficos
Autores principales:	Rouce, Rayne H., Shaim, Hila, Sekine, Takuya, Weber, Gerrit, Ballard, Brandon, Ku, Stephanie, Barese, Cecilia, Murali, Vineeth, Wu, Meng-Fen, Liu, Hao, Shpall, Elizabeth J., Bollard, Catherine M., Rabin, Karen R., Rezvani, Katayoun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823160/ https://www.ncbi.nlm.nih.gov/pubmed/26621337 http://dx.doi.org/10.1038/leu.2015.327

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