Retinal lipid and glucose metabolism dictates angiogenesis through lipid sensor Ffar1

Tissues with high metabolic rates often use lipid as well as glucose for energy, conferring a survival advantage during feast and famine.(1) Current dogma suggests that high-energy consuming photoreceptors depend on glucose.(2,3) Here we show that retina also uses fatty acids (FA) β-oxidation for en...

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Detalles Bibliográficos
Autores principales: Joyal, Jean-Sébastien, Sun, Ye, Gantner, Marin L., Shao, Zhuo, Evans, Lucy P., Saba, Nicholas, Fredrick, Thomas, Burnim, Samuel, Kim, Jin Sung, Patel, Gauri, Juan, Aimee M., Hurst, Christian G., Hatton, Colman J., Cui, Zhenghao, Pierce, Kerry A., Bherer, Patrick, Aguilar, Edith, Powner, Michael B., Vevis, Kristis, Boisvert, Michel, Fu, Zhongjie, Levy, Emile, Fruttiger, Marcus, Packard, Alan, Rezende, Flavio A., Maranda, Bruno, Sapieha, Przemyslaw, Chen, Jing, Friedlander, Martin, Clish, Clary B., Smith, Lois E.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823176/
https://www.ncbi.nlm.nih.gov/pubmed/26974308
http://dx.doi.org/10.1038/nm.4059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823176/
https://www.ncbi.nlm.nih.gov/pubmed/26974308
http://dx.doi.org/10.1038/nm.4059

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