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Rho Kinase Pathway Alterations in the Brain and Leukocytes in Huntington’s Disease

Huntington’s disease (HD) is a fatal neurodegenerative disease caused by an expanded polyglutamine tract in the huntingtin gene. Therapeutic approaches targeting mutant huntingtin (mtHtt) or its downstream toxic consequences are under development, including Rho kinase pathway inhibition. We investig...

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Detalles Bibliográficos
Autores principales:	Narayanan, K. Lakshmi, Chopra, Vanita, Rosas, H. Diana, Malarick, Keith, Hersch, Steven
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823347/ https://www.ncbi.nlm.nih.gov/pubmed/25941073 http://dx.doi.org/10.1007/s12035-015-9147-9

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