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Designing synthetic RNAs to determine the relevance of structural motifs in picornavirus IRES elements

The function of Internal Ribosome Entry Site (IRES) elements is intimately linked to their RNA structure. Viral IRES elements are organized in modular domains consisting of one or more stem-loops that harbor conserved RNA motifs critical for internal initiation of translation. A conserved motif is t...

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Detalles Bibliográficos
Autores principales:	Fernandez-Chamorro, Javier, Lozano, Gloria, Garcia-Martin, Juan Antonio, Ramajo, Jorge, Dotu, Ivan, Clote, Peter, Martinez-Salas, Encarnacion
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823658/ https://www.ncbi.nlm.nih.gov/pubmed/27053355 http://dx.doi.org/10.1038/srep24243

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