Deficiency of the TLR4 analogue RP105 aggravates vein graft disease by inducing a pro-inflammatory response

Venous grafts are often used to bypass occlusive atherosclerotic lesions; however, poor patency leads to vein graft disease. Deficiency of TLR4, an inflammatory regulator, reduces vein graft disease. Here, we investigate the effects of the accessory molecule and TLR4 analogue RadioProtective 105 (RP...

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Detalles Bibliográficos
Autores principales: Wezel, Anouk, de Vries, Margreet R., Maassen, Johanna M., Kip, Peter, Peters, Erna A., Karper, Jacco C., Kuiper, Johan, Bot, Ilze, Quax, Paul H. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823661/
https://www.ncbi.nlm.nih.gov/pubmed/27053419
http://dx.doi.org/10.1038/srep24248

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