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Generation of KCL028 research grade human embryonic stem cell line carrying a mutation in the HTT gene
The KCL028 human embryonic stem cell line was derived from an embryo donated for research that carried an autosomal dominant mutation affecting one allele of the HTT gene encoding huntingtin (43 trinucleotide repeats; 21 for the normal allele). The ICM was isolated using laser microsurgery and plate...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823669/ https://www.ncbi.nlm.nih.gov/pubmed/27345983 http://dx.doi.org/10.1016/j.scr.2016.01.006 |