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Deletion and low expression of NFKBIA are associated with poor prognosis in lower-grade glioma patients

Lower-grade gliomas (LGGs), which are uniformly fatal in young adults, are classified as grades II-III tumors according to their histological features. The NFκB transcription factor, a crucial player in cancer initiation and progression, is inactivated in the cytoplasm by inhibitory proteins (IκBs)...

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Detalles Bibliográficos
Autores principales:	Kinker, Gabriela Sarti, Thomas, Andrew Maltez, Carvalho, Vinicius Jardim, Lima, Felipe Prata, Fujita, André
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823696/ https://www.ncbi.nlm.nih.gov/pubmed/27052952 http://dx.doi.org/10.1038/srep24160

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