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82-kDa choline acetyltransferase and SATB1 localize to β-amyloid induced matrix attachment regions

The M-transcript of human choline acetyltransferase (ChAT) produces an 82-kDa protein (82-kDa ChAT) that concentrates in nuclei of cholinergic neurons. We assessed the effects of acute exposure to oligomeric amyloid-β(1–42) (Aβ(1–42)) on 82-kDa ChAT disposition in SH-SY5Y neural cells, finding that...

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Detalles Bibliográficos
Autores principales: Winick-Ng, Warren, Caetano, Fabiana A., Winick-Ng, Jennifer, Morey, Trevor M., Heit, Bryan, Rylett, R. Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823725/
https://www.ncbi.nlm.nih.gov/pubmed/27052102
http://dx.doi.org/10.1038/srep23914