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Helical X-ray phase-contrast computed tomography without phase stepping

X-ray phase-contrast computed tomography (PCCT) using grating interferometry provides enhanced soft-tissue contrast. The possibility to use standard polychromatic laboratory sources enables an implementation into a clinical setting. Thus, PCCT has gained significant attention in recent years. Howeve...

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Autores principales: Marschner, M., Willner, M., Potdevin, G., Fehringer, A., Noël, P. B., Pfeiffer, F., Herzen, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823776/
https://www.ncbi.nlm.nih.gov/pubmed/27052368
http://dx.doi.org/10.1038/srep23953
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author Marschner, M.
Willner, M.
Potdevin, G.
Fehringer, A.
Noël, P. B.
Pfeiffer, F.
Herzen, J.
author_facet Marschner, M.
Willner, M.
Potdevin, G.
Fehringer, A.
Noël, P. B.
Pfeiffer, F.
Herzen, J.
author_sort Marschner, M.
collection PubMed
description X-ray phase-contrast computed tomography (PCCT) using grating interferometry provides enhanced soft-tissue contrast. The possibility to use standard polychromatic laboratory sources enables an implementation into a clinical setting. Thus, PCCT has gained significant attention in recent years. However, phase-contrast CT scans still require significantly increased measurement times in comparison to conventional attenuation-based CT imaging. This is mainly due to a time-consuming stepping of a grating, which is necessary for an accurate retrieval of the phase information. In this paper, we demonstrate a novel scan technique, which directly allows the determination of the phase signal without a phase-stepping procedure. The presented work is based on moiré fringe scanning, which allows fast data acquisition in radiographic applications such as mammography or in-line product analysis. Here, we demonstrate its extension to tomography enabling a continuous helical sample rotation as routinely performed in clinical CT systems. Compared to standard phase-stepping techniques, the proposed helical fringe-scanning procedure enables faster measurements, an extended field of view and relaxes the stability requirements of the system, since the gratings remain stationary. Finally, our approach exceeds previously introduced methods by not relying on spatial interpolation to acquire the phase-contrast signal.
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spelling pubmed-48237762016-04-18 Helical X-ray phase-contrast computed tomography without phase stepping Marschner, M. Willner, M. Potdevin, G. Fehringer, A. Noël, P. B. Pfeiffer, F. Herzen, J. Sci Rep Article X-ray phase-contrast computed tomography (PCCT) using grating interferometry provides enhanced soft-tissue contrast. The possibility to use standard polychromatic laboratory sources enables an implementation into a clinical setting. Thus, PCCT has gained significant attention in recent years. However, phase-contrast CT scans still require significantly increased measurement times in comparison to conventional attenuation-based CT imaging. This is mainly due to a time-consuming stepping of a grating, which is necessary for an accurate retrieval of the phase information. In this paper, we demonstrate a novel scan technique, which directly allows the determination of the phase signal without a phase-stepping procedure. The presented work is based on moiré fringe scanning, which allows fast data acquisition in radiographic applications such as mammography or in-line product analysis. Here, we demonstrate its extension to tomography enabling a continuous helical sample rotation as routinely performed in clinical CT systems. Compared to standard phase-stepping techniques, the proposed helical fringe-scanning procedure enables faster measurements, an extended field of view and relaxes the stability requirements of the system, since the gratings remain stationary. Finally, our approach exceeds previously introduced methods by not relying on spatial interpolation to acquire the phase-contrast signal. Nature Publishing Group 2016-04-07 /pmc/articles/PMC4823776/ /pubmed/27052368 http://dx.doi.org/10.1038/srep23953 Text en Copyright © 2016, Macmillan Publishers Limited http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Marschner, M.
Willner, M.
Potdevin, G.
Fehringer, A.
Noël, P. B.
Pfeiffer, F.
Herzen, J.
Helical X-ray phase-contrast computed tomography without phase stepping
title Helical X-ray phase-contrast computed tomography without phase stepping
title_full Helical X-ray phase-contrast computed tomography without phase stepping
title_fullStr Helical X-ray phase-contrast computed tomography without phase stepping
title_full_unstemmed Helical X-ray phase-contrast computed tomography without phase stepping
title_short Helical X-ray phase-contrast computed tomography without phase stepping
title_sort helical x-ray phase-contrast computed tomography without phase stepping
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823776/
https://www.ncbi.nlm.nih.gov/pubmed/27052368
http://dx.doi.org/10.1038/srep23953
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