Cargando…

Sepsis-induced long-term immune paralysis – results of a descriptive, explorative study

BACKGROUND: Long-lasting impairment of the immune system is believed to be the underlying reason for delayed deaths after surviving sepsis. We tested the hypothesis of persisting changes to the immune system in survivors of sepsis for the first time. METHODS: In our prospective, cross-sectional pilo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Arens, C., Bajwa, S. A., Koch, C., Siegler, B. H., Schneck, E., Hecker, A., Weiterer, S., Lichtenstern, C., Weigand, M. A., Uhle, F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823837/ https://www.ncbi.nlm.nih.gov/pubmed/27056672 http://dx.doi.org/10.1186/s13054-016-1233-5

Ejemplares similares

Impact of human sepsis on CCCTC-binding factor associated monocyte transcriptional response of Major Histocompatibility Complex II components
por: Siegler, Benedikt Hermann, et al.
Publicado: (2018)

Postoperative abdominal sepsis induces selective and persistent changes in CTCF binding within the MHC-II region of human monocytes
por: Siegler, Benedikt Hermann, et al.
Publicado: (2021)

Sepsis Induces Specific Changes in Histone Modification Patterns in Human Monocytes
por: Weiterer, Sebastian, et al.
Publicado: (2015)

Sepsis in mechanically ventilated patients with spinal cord injury: a retrospective analysis
por: Weiterer, Sebastian, et al.
Publicado: (2018)

Effects of echinocandin preparations on adult rat ventricular cardiomyocytes: Preliminary results of an in vitro study
por: Arens, C., et al.
Publicado: (2014)

Delta-like canonical Notch ligand 1 is predictive for sepsis and acute kidney injury in surgical intensive care patients
por: Schneck, Emmanuel, et al.
Publicado: (2022)

Galactomannan and Zymosan Block the Epinephrine-Induced Particle Transport in Tracheal Epithelium
por: Weiterer, Sebastian, et al.
Publicado: (2015)

Perioperatives Flüssigkeitsmanagement bei großen viszeralchirurgischen Eingriffen
por: von der Forst, M., et al.
Publicado: (2020)

The impact of early surgical intervention in free intestinal perforation: a time-to-intervention pilot study
por: Hecker, Andreas, et al.
Publicado: (2015)

Host-Derived Delta-Like Canonical Notch Ligand 1 as a Novel Diagnostic Biomarker for Bacterial Sepsis—Results From a Combinational Secondary Analysis
por: Hildebrand, Dagmar, et al.
Publicado: (2019)

The Glyoxalase System and Methylglyoxal-Derived Carbonyl Stress in Sepsis: Glycotoxic Aspects of Sepsis Pathophysiology
por: Schmoch, Thomas, et al.
Publicado: (2017)

The immunosuppressive face of sepsis early on intensive care unit—A large-scale microarray meta-analysis
por: Schaack, Dominik, et al.
Publicado: (2018)

From Human Monocytes to Genome-Wide Binding Sites - A Protocol for Small Amounts of Blood: Monocyte Isolation/ChIP-Protocol/Library Amplification/Genome Wide Computational Data Analysis
por: Weiterer, Sebastian, et al.
Publicado: (2014)

Role of the RAGE Axis during the Immune Response after Severe Trauma: A Prospective Pilot Study
por: Uhle, Florian, et al.
Publicado: (2015)

Tumor Necrosis Factor Alpha Induces a Serotonin Dependent Early Increase in Ciliary Beat Frequency and Epithelial Transport Velocity in Murine Tracheae
por: Weiterer, Sebastian, et al.
Publicado: (2014)

Sepsis in der prähospitalen Notfallmedizin: Was können prähospital Tätige aus der Surviving Sepsis Campaign und S3-Leitlinie ziehen?
por: Obermaier, Manuel, et al.
Publicado: (2021)

Early Respiratory Impairment and Pneumonia after Hybrid Laparoscopically Assisted Esophagectomy—A Comparison with the Open Approach
por: Reichert, Martin, et al.
Publicado: (2020)

Comparison of machine-learning methodologies for accurate diagnosis of sepsis using microarray gene expression data
por: Schaack, Dominik, et al.
Publicado: (2021)

Low-Density Granulocyte Contamination From Peripheral Blood Mononuclear Cells of Patients With Sepsis and How to Remove It – A Technical Report
por: Schenz, Judith, et al.
Publicado: (2021)

Delta-Like Canonical Notch Ligand 1 in Patients Following Liver Transplantation—A Secondary Analysis of a Prospective Cohort Study
por: Decker, Sebastian O., et al.
Publicado: (2020)

Abdominal surgery induces long-lasting changes in expression and binding of CTCF with impact on Major Histocompatibility Complex II transcription in circulating human monocytes
por: Siegler, Benedikt Hermann, et al.
Publicado: (2023)

Sepsis Induces a Long-Lasting State of Trained Immunity in Bone Marrow Monocytes
por: Bomans, Katharina, et al.
Publicado: (2018)

Monocyte Metabolism and Function in Patients Undergoing Cardiac Surgery
por: Mayer, Daniel, et al.
Publicado: (2022)

Central sympatholytics prolong survival in experimental sepsis
por: Hofer, Stefan, et al.
Publicado: (2009)

Ivor Lewis esophagectomy patients are particularly vulnerable to respiratory impairment - a comparison to major lung resection
por: Reichert, Martin, et al.
Publicado: (2019)

Caspofungin induces the release of Ca(2+) ions from internal stores by activating ryanodine receptor-dependent pathways in human tracheal epithelial cells
por: Müller, Sabrina, et al.
Publicado: (2020)

Paternal sepsis induces alterations of the sperm methylome and dampens offspring immune responses—an animal study
por: Bomans, Katharina, et al.
Publicado: (2018)

Long-term results of diaphragmatic plication in adults with unilateral diaphragm paralysis
por: Celik, Sezai, et al.
Publicado: (2010)

Evaluation of Long-Term Results of Oberlin Surgery in Obstetric Brachial Paralysis
por: Figueiredo, Eduardo Araújo, et al.
Publicado: (2022)

Intensivtherapie nach Transplantation solider Organe
por: Lichtenstern, C., et al.
Publicado: (2010)

Echinocandins Accelerate Particle Transport Velocity in the Murine Tracheal Epithelium: Dependency on Intracellular Ca(2+) Stores
por: Müller, Sabrina, et al.
Publicado: (2021)

Granulocytic Sarcoma Presenting as Atypical Mastoiditis with Facial Paralysis: Description of a Case
por: Crovetto, M., et al.
Publicado: (2011)

Vocal cord paralysis as primary and secondary results of malignancy. A prospective descriptive study
por: Knudsen, Roi, et al.
Publicado: (2019)

Redox Responses in Patients with Sepsis: High Correlation of Thioredoxin-1 and Macrophage Migration Inhibitory Factor Plasma Levels
por: Brenner, Thorsten, et al.
Publicado: (2010)

Detection of In Vivo Inflammasome Activation for Predicting Sepsis Mortality
por: Cui, Jing, et al.
Publicado: (2021)

The early antibiotic therapy in septic patients - milestone or sticking point?
por: Bernhard, Michael, et al.
Publicado: (2014)

Impact of a semi-structured briefing on the management of adverse events in anesthesiology: a randomized pilot study
por: Neuhaus, Christopher, et al.
Publicado: (2019)

Long‐term efficacy and safety of dichlorphenamide for treatment of primary periodic paralysis
por: Sansone, Valeria A., et al.
Publicado: (2021)

Long-term outcome and prognosis of dissociative disorder with onset in childhood or adolescence
por: Jans, Thomas, et al.
Publicado: (2008)

Preoperative neutrophil to lymphocyte ratio and platelet to lymphocyte ratio are associated with major adverse cardiovascular and cerebrovascular events in coronary heart disease patients undergoing non-cardiac surgery
por: Larmann, Jan, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_5s47u0dnd8gockatp6fgvnppi4