Escherichia coli-based production of recombinant ovine angiotensinogen and its characterization as a renin substrate

BACKGROUND: Angiotensinogen (ANG) is a macromolecular precursor of angiotensin, which regulates blood pressure and electrolyte balance. ANG is specifically cleaved by renin, an aspartic protease, to initiate the angiotensin-processing cascade. Ovine ANG (oANG) from sheep plasma has been shown to be...

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Detalles Bibliográficos
Autores principales: Yamashita, Shinji, Shibata, Naoya, Boku-Ikeda, Akiyoshi, Abe, Erika, Inayama, Ayumi, Yamaguchi, Takashi, Higuma, Ayano, Inagaki, Kaoru, Tsuyuzaki, Tomoyo, Iwamoto, Satoshi, Ohno, Satoshi, Yokogawa, Takashi, Nishikawa, Kazuya, Biswas, Kazal Boron, Nabi, A. H. M. Nurun, Nakagawa, Tsutomu, Suzuki, Fumiaki, Ebihara, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823841/
https://www.ncbi.nlm.nih.gov/pubmed/27052373
http://dx.doi.org/10.1186/s12896-016-0265-x

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