Complement activation at the motor end-plates in amyotrophic lateral sclerosis

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a fatal progressive neurodegenerative disease with no available therapy. Components of the innate immune system are activated in the spinal cord and central nervous system of ALS patients. Studies in the SOD1(G93A) mouse show deposition of C1q and C...

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Detalles Bibliográficos
Autores principales: Bahia El Idrissi, Nawal, Bosch, Sanne, Ramaglia, Valeria, Aronica, Eleonora, Baas, Frank, Troost, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823861/
https://www.ncbi.nlm.nih.gov/pubmed/27056040
http://dx.doi.org/10.1186/s12974-016-0538-2

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