PML-RAR alpha induces the downmodulation of HHEX: a key event responsible for the induction of an angiogenetic response

BACKGROUND: Recent studies indicate that angiogenesis is important in the pathogenesis of acute myeloid leukemias (AMLs). Among the various AMLs, the bone marrow angiogenetic response is particularly pronounced in acute promyelocytic leukemia (APL). However, the molecular mechanisms responsible for...

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Detalles Bibliográficos
Autores principales: Saulle, Ernestina, Petronelli, Alessia, Pelosi, Elvira, Coppotelli, Elena, Pasquini, Luca, Ilari, Ramona, Lo-Coco, Francesco, Testa, Ugo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823896/
https://www.ncbi.nlm.nih.gov/pubmed/27052408
http://dx.doi.org/10.1186/s13045-016-0262-5

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