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Computing the origin and evolution of the ribosome from its structure — Uncovering processes of macromolecular accretion benefiting synthetic biology

Accretion occurs pervasively in nature at widely different timeframes. The process also manifests in the evolution of macromolecules. Here we review recent computational and structural biology studies of evolutionary accretion that make use of the ideographic (historical, retrodictive) and nomotheti...

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Detalles Bibliográficos
Autores principales: Caetano-Anollés, Gustavo, Caetano-Anollés, Derek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823900/
https://www.ncbi.nlm.nih.gov/pubmed/27096056
http://dx.doi.org/10.1016/j.csbj.2015.07.003