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Characterizing heterogeneity in the response of synovial mesenchymal progenitor cells to synovial macrophages in normal individuals and patients with osteoarthritis
BACKGROUND: Resident macrophages in OA synovial tissue contribute to synovitis through pro-inflammatory mediators driving cartilage loss. What remains unknown is how these macrophages interact with synovial mesenchymal progenitor cells (sMPCs) in the joint. sMPCs have the potential to undergo chondr...
Autores principales: | Fichadiya, Akash, Bertram, Karri L, Ren, Guomin, Yates, Robin M, Krawetz, Roman J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823907/ https://www.ncbi.nlm.nih.gov/pubmed/27057150 http://dx.doi.org/10.1186/s12950-016-0120-9 |
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