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Alkaline ceramidase 3 deficiency aggravates colitis and colitis-associated tumorigenesis in mice by hyperactivating the innate immune system

Increasing studies suggest that ceramides differing in acyl chain length and/or degree of unsaturation have distinct roles in mediating biological responses. However, still much remains unclear about regulation and role of distinct ceramide species in the immune response. Here, we demonstrate that a...

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Detalles Bibliográficos
Autores principales:	Wang, K, Xu, R, Snider, A J, Schrandt, J, Li, Y, Bialkowska, A B, Li, M, Zhou, J, Hannun, Y A, Obeid, L M, Yang, V W, Mao, C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823937/ https://www.ncbi.nlm.nih.gov/pubmed/26938296 http://dx.doi.org/10.1038/cddis.2016.36

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