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IL10 inhibits starvation-induced autophagy in hypertrophic scar fibroblasts via cross talk between the IL10-IL10R-STAT3 and IL10-AKT-mTOR pathways
Hypertrophic scar (HS) is a serious skin fibrotic disease characterized by excessive hypercellularity and extracellular matrix (ECM) component deposition. Autophagy is a tightly regulated physiological process essential for cellular maintenance, differentiation, development, and homeostasis. Previou...
Autores principales: | Shi, J, Wang, H, Guan, H, Shi, S, Li, Y, Wu, X, Li, N, Yang, C, Bai, X, Cai, W, Yang, F, Wang, X, Su, L, Zheng, Z, Hu, D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823945/ https://www.ncbi.nlm.nih.gov/pubmed/26962683 http://dx.doi.org/10.1038/cddis.2016.44 |
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