Inhibition of glycogen synthase kinase 3β promotes autophagy to protect mice from acute liver failure mediated by peroxisome proliferator-activated receptor α

Our previous studies have demonstrated that inhibition of glycogen synthase kinase 3β (GSK3β) activity protects mice from acute liver failure (ALF), whereas its protective and regulatory mechanism remains elusive. Autophagy is a recently recognized rudimentary cellular response to inflammation and i...

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Detalles Bibliográficos
Autores principales: Ren, F, Zhang, L, Zhang, X, Shi, H, Wen, T, Bai, L, Zheng, S, Chen, Y, Chen, D, Li, L, Duan, Z
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823957/
https://www.ncbi.nlm.nih.gov/pubmed/27010852
http://dx.doi.org/10.1038/cddis.2016.56

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