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Dihydroartemisinin attenuates lipopolysaccharide-induced osteoclastogenesis and bone loss via the mitochondria-dependent apoptosis pathway

Dihydroartemisinin (DHA) is a widely used antimalarial drug isolated from the plant Artemisia annua. Recent studies suggested that DHA has antitumor effects utilizing its reactive oxygen species (ROS) yielding mechanism. Here, we reported that DHA is inhibitory on lipopolysaccharide (LPS)-induced os...

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Detalles Bibliográficos
Autores principales: Dou, C, Ding, N, Xing, J, Zhao, C, Kang, F, Hou, T, Quan, H, Chen, Y, Dai, Q, Luo, F, Xu, J, Dong, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823966/
https://www.ncbi.nlm.nih.gov/pubmed/27031959
http://dx.doi.org/10.1038/cddis.2016.69