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Atlas of Cryptic Genetic Relatedness Among 1000 Human Genomes

A novel computational method for detecting identical-by-descent (IBD) chromosomal segments between sequenced genomes is presented. It utilizes the distribution patterns of very rare genetic variants (vrGVs), which have minor allele frequencies <0.2%. Contrary to the existing probabilistic approac...

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Detalles Bibliográficos
Autores principales:	Fedorova, Larisa, Qiu, Shuhao, Dutta, Rajib, Fedorov, Alexei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824066/ https://www.ncbi.nlm.nih.gov/pubmed/26907499 http://dx.doi.org/10.1093/gbe/evw034

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