The long noncoding RNA Gm15055 represses Hoxa gene expression by recruiting PRC2 to the gene cluster

The Hox genes encode transcription factors that determine embryonic pattern formation. In embryonic stem cells, the Hox genes are silenced by PRC2. Recent studies have reported a role for long noncoding RNAs in PRC2 recruitment in vertebrates. However, little is known about how PRC2 is recruited to...

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Detalles Bibliográficos
Autores principales: Liu, Guo-You, Zhao, Guang-Nian, Chen, Xiao-Feng, Hao, De-Long, Zhao, Xiang, Lv, Xiang, Liu, De-Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824075/
https://www.ncbi.nlm.nih.gov/pubmed/26615201
http://dx.doi.org/10.1093/nar/gkv1315

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824075/
https://www.ncbi.nlm.nih.gov/pubmed/26615201
http://dx.doi.org/10.1093/nar/gkv1315

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