Natural antisense RNA promotes 3′ end processing and maturation of MALAT1 lncRNA

The RNase P-mediated endonucleolytic cleavage plays a crucial role in the 3′ end processing and cellular accumulation of MALAT1, a nuclear-retained long noncoding RNA that promotes malignancy. The regulation of this cleavage event is largely undetermined. Here we characterize a broadly expressed nat...

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Detalles Bibliográficos
Autores principales: Zong, Xinying, Nakagawa, Shinichi, Freier, Susan M., Fei, Jingyi, Ha, Taekjip, Prasanth, Supriya G., Prasanth, Kannanganattu V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824109/
https://www.ncbi.nlm.nih.gov/pubmed/26826711
http://dx.doi.org/10.1093/nar/gkw047

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