Genetic Load of Loss-of-Function Polymorphic Variants in Great Apes

Loss of function (LoF) genetic variants are predicted to disrupt gene function, and are therefore expected to substantially reduce individual’s viability. Knowing the genetic burden of LoF variants in endangered species is of interest for a better understanding of the effects of declining population...

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Detalles Bibliográficos
Autores principales: de Valles-Ibáñez, Guillem, Hernandez-Rodriguez, Jessica, Prado-Martinez, Javier, Luisi, Pierre, Marquès-Bonet, Tomàs, Casals, Ferran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824148/
https://www.ncbi.nlm.nih.gov/pubmed/26912403
http://dx.doi.org/10.1093/gbe/evw040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824148/
https://www.ncbi.nlm.nih.gov/pubmed/26912403
http://dx.doi.org/10.1093/gbe/evw040

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