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How Soluble GARP Enhances TGFβ Activation

GARP (glycoprotein A repetitions predominant) is a cell surface receptor on regulatory T-lymphocytes, platelets, hepatic stellate cells and certain cancer cells. Its described function is the binding and accommodation of latent TGFβ (transforming growth factor), before the activation and release of...

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Detalles Bibliográficos
Autores principales: Fridrich, Sven, Hahn, Susanne A., Linzmaier, Marion, Felten, Matthias, Zwarg, Jenny, Lennerz, Volker, Tuettenberg, Andrea, Stöcker, Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824412/
https://www.ncbi.nlm.nih.gov/pubmed/27054568
http://dx.doi.org/10.1371/journal.pone.0153290