Cargando…
How Soluble GARP Enhances TGFβ Activation
GARP (glycoprotein A repetitions predominant) is a cell surface receptor on regulatory T-lymphocytes, platelets, hepatic stellate cells and certain cancer cells. Its described function is the binding and accommodation of latent TGFβ (transforming growth factor), before the activation and release of...
Autores principales: | Fridrich, Sven, Hahn, Susanne A., Linzmaier, Marion, Felten, Matthias, Zwarg, Jenny, Lennerz, Volker, Tuettenberg, Andrea, Stöcker, Walter |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824412/ https://www.ncbi.nlm.nih.gov/pubmed/27054568 http://dx.doi.org/10.1371/journal.pone.0153290 |
Ejemplares similares
-
A key role of GARP in the immune suppressive tumor microenvironment
por: Hahn, Susanne A., et al.
Publicado: (2016) -
GARP regulates the bioavailability and activation of TGFβ
por: Wang, Rui, et al.
Publicado: (2012) -
Rhinovirus Suppresses TGF-β-GARP Presentation by Peripheral NK Cells
por: Krammer, Susanne, et al.
Publicado: (2022) -
GARP as an Immune Regulatory Molecule in the Tumor Microenvironment of Glioblastoma Multiforme
por: Zimmer, Niklas, et al.
Publicado: (2019) -
Immunoregulatory functions and the therapeutic implications of GARP-TGF-β in inflammation and cancer
por: Metelli, Alessandra, et al.
Publicado: (2018)