Deceased-Donor Apolipoprotein L1 Renal-Risk Variants Have Minimal Effects on Liver Transplant Outcomes

BACKGROUND: Apolipoprotein L1 gene (APOL1) G1 and G2 renal-risk variants, common in populations with recent African ancestry, are strongly associated with non-diabetic nephropathy, end-stage kidney disease, and shorter allograft survival in deceased-donor kidneys (autosomal recessive inheritance). C...

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Detalles Bibliográficos
Autores principales: Dorr, Casey R., Freedman, Barry I., Hicks, Pamela J., Brown, W. Mark, Russell, Gregory B., Julian, Bruce A., Pastan, Stephen O., Gautreaux, Michael D., Muthusamy, Amutha, Chinnakotla, Srinath, Hauptfeld, Vera, Bray, Robert A., Kirk, Allan D., Divers, Jasmin, Israni, Ajay K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824450/
https://www.ncbi.nlm.nih.gov/pubmed/27054572
http://dx.doi.org/10.1371/journal.pone.0152775

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