Nanoscale Reaction Vessels Designed for Synthesis of Copper-Drug Complexes Suitable for Preclinical Development

The development of copper-drug complexes (CDCs) is hindered due to their very poor aqueous solubility. Diethyldithiocarbamate (DDC) is the primary metabolite of disulfiram, an approved drug for alcoholism that is being repurposed for cancer. The anticancer activity of DDC is dependent on complexatio...

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Detalles Bibliográficos
Autores principales: Wehbe, Mohamed, Anantha, Malathi, Backstrom, Ian, Leung, Ada, Chen, Kent, Malhotra, Armaan, Edwards, Katarina, Bally, Marcel B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824478/
https://www.ncbi.nlm.nih.gov/pubmed/27055237
http://dx.doi.org/10.1371/journal.pone.0153416

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824478/
https://www.ncbi.nlm.nih.gov/pubmed/27055237
http://dx.doi.org/10.1371/journal.pone.0153416

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