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Revisiting the Middle Molecule Hypothesis of Uremic Toxicity: A Systematic Review of Beta 2 Microglobulin Population Kinetics and Large Scale Modeling of Hemodialysis Trials In Silico

BACKGROUND: Beta-2 Microglobulin (β2M) is a prototypical “middle molecule” uremic toxin that has been associated with a higher risk of death in hemodialysis patients. A quantitative description of the relative importance of factors determining β2M concentrations among patients with impaired kidney f...

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Detalles Bibliográficos
Autores principales:	Roumelioti, Maria Eleni, Nolin, Thomas, Unruh, Mark L., Argyropoulos, Christos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824495/ https://www.ncbi.nlm.nih.gov/pubmed/27055286 http://dx.doi.org/10.1371/journal.pone.0153157

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