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MAPK15 mediates BCR-ABL1-induced autophagy and regulates oncogene-dependent cell proliferation and tumor formation

A reciprocal translocation of the ABL1 gene to the BCR gene results in the expression of the oncogenic BCR-ABL1 fusion protein, which characterizes human chronic myeloid leukemia (CML), a myeloproliferative disorder considered invariably fatal until the introduction of the imatinib family of tyrosin...

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Detalles Bibliográficos
Autores principales:	Colecchia, David, Rossi, Matteo, Sasdelli, Federica, Sanzone, Sveva, Strambi, Angela, Chiariello, Mario
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2015
Materias:	Basic Research Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824572/ https://www.ncbi.nlm.nih.gov/pubmed/26291129 http://dx.doi.org/10.1080/15548627.2015.1084454

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