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The activation of KSHV lytic cycle blocks autophagy in PEL cells

This study confirms that autophagy is activated concomitantly with KSHV lytic cycle induction, and that autophagy inhibition by BECN1 knockdown reduces viral lytic gene expression. In addition, we extend previous observations and show that autophagy is blocked at late steps, during viral replication...

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Detalles Bibliográficos
Autores principales:	Granato, Marisa, Santarelli, Roberta, Filardi, Mariarosaria, Gonnella, Roberta, Farina, Antonella, Torrisi, Maria Rosaria, Faggioni, Alberto, Cirone, Mara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2015
Materias:	Basic Brief Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824593/ https://www.ncbi.nlm.nih.gov/pubmed/26391343 http://dx.doi.org/10.1080/15548627.2015.1091911

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